Little has changed in our medical treatment for the most common Bone Sarcoma in children, Osteosarcoma, over the past 30+ years. Several phase I trials and translational studies show promise for those patients battling relapsed or progressive disease. A phase II COG trial is about to open for relapsing patients using Denosumab in combination with other agents. Details of the study can
https://clinicaltrials.gov/ct2/show/NCT02470091
