Gut microbiome and immunotherapy

There is a growing appreciation of the role of the trillions of bacteria found in our gut, referred to as the gut microbiome, in relationship to health and disease.  In mice, it has been shown that you can modulate the gut microbiome to enhance the mouse’s response to immunotherapy.  In the cancer network story below Dr. Wargo shares how she saw similar results in patients with metastatic melanoma.  Brings up several intriguing questions and possible ways to enhance the effect of immunotherapy treatments that are becoming more popular in all cancer types, including sarcoma.




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